Remember the game for Nintendo called "De Ja Vu?"
You play as detective Ace Harding, trying to solve a murder despite the fact that your memory has been erased, but you have to find an antidote to restore your mind and solve the crime... Look who I have as Ace Harding!
Source images: Google, Flickr, Yahoo
The rest: Photoshop
Don't sue me for copyright infringement, this is just a fan made design of mine...

©2010 Angry Dog Designs, Inc.
I was thinking more along the lines of Bruce Willis. :V He was a boxer in the game, y'know. Depp ain't got the physique. xD
Nice mash-up, though.
And your poster is really great!